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| Category: |
Science |
| Word Count: |
387 |
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Benzamide
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In 1986 Richard Gedye and coworkers published a short communication in Tetrahedron Letters, entitled "The Use Of Microwave Ovens for Rapid Organic Synthesis" which for the first time described the utilization and advantages of microwave irradiation for organic synthesis [1,2]. In this original publication [1] four different types of reactions were studied, including the hydrolysis of benzamide to benzoic acid under acidic conditions (Scheme 1). Considerable rate increases (5 - 1000 fold) were ob
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