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Category: Science
Word Count: 1626
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Neuronal Differentiation of PC12

Abstract: Neuronal differentiation of PC12 cells can be useful to test several different treatments to investigate which promote neuronal outgrowth and which do not. PC12 cells are a clonal line derived from a rat pheochromocytoma in the adrenal medulla (). This experiment was designed to prove that Nerve Growth Factor (NGF) is a strong promoter and can be reinforced with dibutyryl cyclic AMP (dbcAMP), which is a second messenger. An Epidermal Growth Factor (EGF) was also tested as well as Methy

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